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HomeCultureIn Vitro Development Competence of Ovine Oocytes

In Vitro Development Competence of Ovine Oocytes


In 1878, the first case of in vitro fertilization (IVF) was conducted by Schenk with the first documented birth of rabbit via the technology of IVF-embryo transfer (ET) achieved by Walter Heape in 1959,1 benefiting the applications of assisted reproductive technologies (ARTs) in mammalian breeding via the in vitro production (IVP) of mammalian embryos during the past decades. With the promising development of ARTs, the technologies including ovum pick-up (OPU), in vitro maturation (IVM), IVF, cryobiology of mammalian gametes and ET not only promote these in vitro research related to gametogenesis, stem cells, and developmental biology,2 but also offer new alternatives for the fertility preservation for patients undergoing cancer treatments and reproductive failures.

Nevertheless, the ARTs applied for livestock and human beings lack the complex ovarian microenvironments in vivo, which are necessary for the in vivo processes of…

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